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Every AI Founder Should Be Asking These Questions

As artificial intelligence accelerates toward human-level performance, startup founders are confronted with unprecedented strategic uncertainty. The rapid evolution of AI systems forces a reevaluation of traditional assumptions about product development, team structure, and long-term viability. In this pivotal moment, the most pressing challenge isn't technological—it's existential: how should entrepreneurs make decisions when the rules of the game could change overnight?
The podcast explores how startups must adapt to an era where AGI may emerge within years, not decades. Founders need to question whether to launch companies at all, as AI commoditizes software and reshapes enterprise needs. AI-native products are favored over retrofitted ones, while trust becomes harder to maintain in small, automated teams—prompting proposals for AI-powered auditing. Though custom data once offered advantage, its value is eroding, pushing defensibility toward hard infrastructure like energy and chip development. Founders are urged to focus on societal impact and long-term vision amid shifting economic structures. Meanwhile, venture capital lags in understanding AI’s implications, underestimating the complexity of AI agent interactions and the urgent need for new trust mechanisms in autonomous systems.
02:22
02:22
Founders should plan for AGI within two years.
13:54
13:54
AI can enable less biased, memory-free auditing to build trust in startups.
21:00
21:00
Working on hard problems like energy and manufacturing could be a key moat in the future of AI
25:25
25:25
This is the last chance to make a world-changing impact with AI
39:23
39:23
A personal assistant agent must handle game theory and power dynamics in scheduling.