Tim Ferriss shares how childhood trauma and genetic predisposition led to severe depression, prompting him to explore advanced mental health interventions. He highlights accelerated TMS, which delivered rapid relief from anxiety after just five days of intensive treatment, and discusses metabolic psychiatry, where ketogenic diets have helped reduce or eliminate psychiatric medications in some cases. Psychedelic-assisted therapy, particularly with MDMA, has shown transformative potential by reopening neuroplasticity. He emphasizes vagus nerve stimulation as a key tool for improving heart rate variability and calming the nervous system, supported by both implantable and non-invasive devices. Beyond technology, Tim underscores the importance of human connection, warning against the emotional toll of dating apps and the illusion of choice they create. His healing was fueled by creative expression, public storytelling, and confronting suppressed emotions through psychedelics and therapy. Ultimately, he advocates for identifying root causes of mental distress—not just managing symptoms—and prioritizing meaningful relationships as foundational to well-being.