Uncapped #27 | Vince Hankes from Thrive Capital
Uncapped #27 | Vince Hankes from Thrive Capital
Uncapped #27 | Vince Hankes from Thrive Capital
In this episode, Vince Hankes of Thrive Capital shares insights into the firm's unique investment philosophy and its evolution into one of the most influential players in venture capital. From early bets on now-iconic tech companies to deploying billion-dollar checks with unwavering conviction, the conversation dives into the mindset behind high-impact investing in transformative technologies.
Thrive Capital’s success stems from a contrarian, founder-centric approach that prioritizes qualitative insights before quantitative validation. The firm focuses on generational companies like Stripe, Databricks, and OpenAI, often writing massive checks at pivotal growth stages where few competitors can operate. Its barbell strategy—investing either very early or in dominant platforms—avoids crowded mid-stage markets. Bold moves, such as doubling down on Carvana during a steep decline, reflect a culture of conviction and long-term compounding. While AI is expected to augment rather than replace human roles, Thrive sees outsized potential in foundational model builders like OpenAI, which remain independent amid pressure from tech giants. Investments in vertical-specific AI and emerging robotics also signal strategic bets on nascent but high-upside sectors. Ultimately, Thrive’s edge lies in a lean, agile structure that enables decisive action, deep founder engagement, and a relentless focus on backing transformative innovation—driven by talent that combines ambition with independent thinking.
06:35
06:35
Invested nearly $2 billion in Stripe in early 2023 despite post-COVID skepticism
09:39
09:39
Winners are getting bigger: the number of $100 billion tech companies is growing faster than $10 billion ones.
23:39
23:39
Writing billion-dollar checks allows access to exclusive late-stage deals with less competition
28:21
28:21
Doubled shares in Carvana at a low price despite psychological and LP pressure
32:53
32:53
Being the accounting firm is the best way to play accounting in AI.
36:13
36:13
Isomorphic aims to cure all diseases by simulating wet-lab experiments computationally.
44:45
44:45
OpenAI has built significant IP in efficient inference and model infrastructure.
45:19
45:19
Lawyers and doctors are unexpected early adopters of AI due to workflow compatibility and FOMO.
50:00
50:00
Robotics could be at the same stage as self-driving cars in 2015
53:52
53:52
Few opportunities offer a better risk-adjusted return than OpenAI, though risk is unavoidable.
55:59
55:59
Attracting talented and ambitious young people is crucial for Thrive's next phase
