Essentials: Erasing Fears & Traumas Using Modern Neuroscience
Huberman Lab
Nov 06
Essentials: Erasing Fears & Traumas Using Modern Neuroscience
Essentials: Erasing Fears & Traumas Using Modern Neuroscience

Huberman Lab
Nov 06
Shownote
Shownote
In this Huberman Lab Essentials episode, I explore the neuroscience of fear and trauma and how to effectively process and eliminate traumatic responses.
I explain why successful fear treatment requires both extinction of the old fearful response and replacement with a new positive association—not just cognitive reframing. I also explain how the threat reflex activates specific circuits connecting the amygdala, prefrontal cortex, and dopamine systems, and why detailed recounting of traumatic events progressively reduces their physiological impact. Finally, I review evidence-based approaches, including prolonged exposure therapy and cognitive behavioral therapy, discuss how five minutes per day of deliberate stress through cyclic hyperventilation can rewire fear responses, explain the critical role of social connection in activating neural pathways that reduce trauma, and share supplementation options for managing anxiety.
Read the episode show notes at hubermanlab.com.
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Timestamps
(0:00) Introducing Fear & Trauma
(0:17) What is Fear?
(1:03) Autonomic Arousal: "Alertness" vs. "Calmness"
(2:05) Fear vs. Stress & Anxiety
(9:20) "The Threat Reflex": Neural Circuits for Fear
(20:50) Cognitive (Narrative) Therapies for Fear
(26:35) PTSD Treatments: Ketamine, MDMA, Oxytocin
(33:11) Deliberate Brief Stress Can Erase Fears & Trauma
(35:51) Nutrition, Sleep, & Other General Support Erasing Fear & Trauma
(38:18) Recap
Disclaimer & Disclosures
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Highlights
Highlights
This episode delves into the intricate neuroscience behind fear and trauma, examining how the brain encodes and responds to threats on both biological and psychological levels. By exploring the underlying neural mechanisms, the discussion sets the stage for understanding modern, science-backed strategies aimed at dismantling persistent fear responses and promoting lasting emotional resilience.
Chapters
Chapters
Introducing Fear & Trauma
00:00What is Fear?
00:17Autonomic Arousal: "Alertness" vs. "Calmness"
01:03Fear vs. Stress & Anxiety
02:05"The Threat Reflex": Neural Circuits for Fear
09:20Cognitive (Narrative) Therapies for Fear
20:50PTSD Treatments: Ketamine, MDMA, Oxytocin
26:35Deliberate Brief Stress Can Erase Fears & Trauma
33:11Nutrition, Sleep, & Other General Support Erasing Fear & Trauma
35:51Recap
38:18Transcript
Transcript
Andrew Huberman: Welcome to Huberman Lab Essentials, where we revisit past episodes for the most potent and actionable science-based tools for mental health, physical health, and performance. I'm Andrew Huberman, and I'm a professor of neurobiology and oph...