#838: The Random Show — The 2–2–2 Rule, The Future of AI, Bioelectric Medicine, Surviving Modern Dating, The Promises of DORAs for Alzheimer’s, and Wisdom from Anthony de Mello
The Tim Ferriss Show
Dec 03
#838: The Random Show — The 2–2–2 Rule, The Future of AI, Bioelectric Medicine, Surviving Modern Dating, The Promises of DORAs for Alzheimer’s, and Wisdom from Anthony de Mello
#838: The Random Show — The 2–2–2 Rule, The Future of AI, Bioelectric Medicine, Surviving Modern Dating, The Promises of DORAs for Alzheimer’s, and Wisdom from Anthony de Mello
The Tim Ferriss Show
Dec 03
In this wide-ranging conversation, Tim Ferriss and Kevin Rose dive into personal growth, cutting-edge science, and the evolving landscape of technology and relationships. The discussion moves fluidly from mental health innovations to the future of AI, offering candid reflections and forward-thinking insights.
Kevin Rose reflects on ending seven months of sobriety by adopting a mindful 2-2-2 Rule for alcohol consumption. Tim shares his transformative experience with accelerated TMS therapy for anxiety, developed by the late Nolan Williams, whose legacy continues through the Saisei Foundation’s neuroscience research. They explore cognitive diversity, including aphantasia and hyperphantasia, and emphasize sleep's role in preventing Alzheimer’s, discussing DORA medications and metabolic strategies like ketosis. The rapid evolution of AI is examined, with Google’s full-stack advantage and strategic investment areas in power, data centers, and automation highlighted. Kevin details his AI toolkit, while Tim praises Oboe.fyi for personalized learning. Personal updates include Tim’s new relationship, emphasizing communication frameworks over objective truth in conflicts, and pet health advances using rapamycin. The conversation closes with wellness-focused gift ideas and holiday wishes.
00:57
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Abstinence could be a trap, according to insights from 'Awareness' by Anthony de Mello.
07:16
07:16
Five days of accelerated TMS eliminated generalized anxiety for months
21:14
21:14
D-serine plus stimulation shows promising signals in patient cohorts
29:59
29:59
Josh Waitzkin can 'feel' chess moves and once sensed a cheat during simultaneous games
33:12
33:12
Reducing beta amyloid and tau buildup through quality sleep may delay Alzheimer’s progression.
46:22
46:22
Engineers who dismissed AI for coding three months ago now find it vastly improved.
55:50
55:50
At current valuations, the guest wouldn't invest in the top AI companies.
58:05
58:05
CEOs forcing engineers to use AI daily are the ones to watch for AI transformation
1:16:59
1:16:59
The Tank M3 push sled is effective for strength training and back pain relief on any surface
1:24:11
1:24:11
Use NotebookLM to create instant podcast primers on any topic
1:30:03
1:30:03
An investment can still be a win if you gain skills and relationships, even when the company fails.
1:32:12
1:32:12
Modern dating apps are designed to be addictive and undermine relationship commitment through recurring revenue models.
1:38:18
1:38:18
Objective reality has no place in relationship arguments—subjective stories matter more.
1:47:19
1:47:19
Rapamycin resulted in a 20% boost in lifespan for Toaster.
1:50:48
1:50:48
Qlosi is an FDA-approved eyedrop for presbyopia with fast-acting results and mild side effects.
