Ilya & I discuss SSI’s strategy, the problems with pre-training, how to improve the generalization of AI models, and how to ensure AGI goes well. Watch on YouTube; read the transcript. Sponsors * Gemini 3 is the first model I’ve used that can find conne...

As part of this interview, Satya Nadella gave Dylan Patel (founder of SemiAnalysis) and me an exclusive first-look at their brand-new Fairwater 2 datacenter. Microsoft is building multiple Fairwaters, each of which has hundreds of thousands of GB200s & GB...

In this lecture, military historian Sarah Paine explains how Russia—and specifically Stalin—completely derailed China’s rise, slowing them down for over a century. This lecture was particularly interesting to me because, in my opinion, the Chinese Civil W...

The Andrej Karpathy episode. During this interview, Andrej explains why reinforcement learning is terrible (but everything else is much worse), why AGI will just blend into the previous ~2.5 centuries of 2% GDP growth, why self driving took so long to cra...

Nick Lane has some pretty wild ideas about the evolution of life. He thinks early life was continuous with the spontaneous chemistry of undersea hydrothermal vents. Nick’s story may be wrong, but I find it remarkable that with just that starting point, y...

I have a much better understanding of Sutton’s perspective now. I wanted to reflect on it a bit. (00:00:00) - The steelman (00:02:42) - TLDR of my current thoughts (00:03:22) - Imitation learning is continuous with and complementary to RL (00:08:26) - ...

Richard Sutton is the father of reinforcement learning, winner of the 2024 Turing Award, and author of The Bitter Lesson. And he thinks LLMs are a dead end. After interviewing him, my steel man of Richard’s position is this: LLMs aren’t capable of learnin...

Sergey Levine, one of the world’s top robotics researchers and co-founder of Physical Intelligence, thinks we’re on the cusp of a “self-improvement flywheel” for general-purpose robots. His median estimate for when robots will be able to run households ent...

In this lecture, military historian Sarah Paine explains how Britain used sea control, peripheral campaigns, and alliances to defeat Nazi Germany during WWII. She then applies this framework to today, arguing that Russia and China are similarly constrained...

Jacob Kimmel thinks he can find the transcription factors to reverse aging. We do a deep dive on why this might be plausible and why evolution hasn’t optimized for longevity. We also talk about why drug discovery has been getting exponentially harder, and ...

How will we feed the 100s of GWs of extra energy demand that AI will create over the coming decade? On this episode, Casey Handmer (Caltech PhD, former NASA JPL, founder & CEO of Terraform Industries) walks me through how we can pull it off, and why he thi...

A deep dive with Lewis Bollard, who leads Open Philanthropy’s strategy for Farmed Animal Welfare, on the surprising economics of the meat industry. Why is factory farming so efficient? How can we make the lives of the 23+ billion animals living on factor...

After my last lecture series with Sarah Paine ended, I still had so many questions. I knew we’d only scratched the surface of Sarah’s scholarship, so I immediately invited her back for another series: she graciously agreed, and we’ll be releasing the resul...

The Stephen Kotkin episode. Kotkin is arguably the world’s foremost expert on Joseph Stalin and has written a massive 2-volume biography on him (with a 3rd volume in the works). No other individual had more of a profound impact on the 20th century than St...

I’ve had a lot of discussions on my podcast where we haggle out timelines to AGI. Some guests think it’s 20 years away - others 2 years. Here’s an audio version of where my thoughts stand as of June 2025. If you want to read the original post, you can che...

George Church is the godfather of modern synthetic biology and has been involved with basically every major biotech breakthrough in the last few decades. Professor Church thinks that these improvements (e.g., orders of magnitude decrease in sequencing & s...

Arthur Kroeber is a leading researcher on Chinese tech and macro, a founding partner at Gavekal Dragonomics, and author of "China's Economy: What Everyone Needs to Know." It's the most useful, detailed resource I've found of how China actually works. On t...

Ken Rogoff is the former chief economist of the IMF, a professor of Economics at Harvard, and author of the newly released Our Dollar, Your Problem and This Time is Different. On this episode, Ken predicts that, within the next decade, the US will have a ...

On this episode, I chat with Victor Shih about all things China. We discuss China’s massive local debt crisis, the CCP’s views on AI, what happens after Xi, and more. Victor Shih is an expert on the Chinese political system, as well as their banking and f...

New episode with my good friends Sholto Douglas & Trenton Bricken. Sholto focuses on scaling RL and Trenton researches mechanistic interpretability, both at Anthropic. We talk through what’s changed in the last year of AI research; the new RL regime and h...